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Table of Contents for this page:

  • Recent Articles
  • Recent articles from the journal "Virology"

    Note: This list is from Pubmed

    pubmed: virology[journal] 20...

  • Mouse papillomavirus MmuPV1 infects oral mucosa and preferentially targets the base of the tongue.

  • Related Articles

    Mouse papillomavirus MmuPV1 infects oral mucosa and preferentially targets the base of the tongue.

    Virology. 2016 Jan 15;488:73-80

    Authors: Cladel NM, Budgeon LR, Balogh KK, Cooper TK, Hu J, Christensen ND

    Abstract
    In 2010, a new mouse papillomavirus, MmuPV1, was discovered in a colony of NMRI- Foxn1(nu)/Foxn1(nu) athymic mice in India. This finding was significant because it was the first papillomavirus to be found in a laboratory mouse. In this paper we report successful infections of both dorsal and ventral surfaces of the rostral tongues of outbred athymic nude mice. We also report the observation that the base of the tongue, the area of the tongue often targeted by cancer-associated high-risk papillomavirus infections in humans, is especially susceptible to infection. A suitable animal model for the study of oral papillomavirus infections, co-infections, and cancers has long been sought. The work presented here suggests that such a model is now at hand.

    PMID: 26609937 [PubMed - indexed for MEDLINE]

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