About viruses and viral disease
Sun, 26 Jul 2015 15:10:10 +0000
TWiV 347: Rose rosette and squirrel roulette
On episode #347 of the science show This Week in Virology, Vincent, Alan, and Rich discuss the virus behind rose rosette disease, and fatal human encephalitis caused by a variegated squirrel bornavirus. You can find TWiV #347 at www.twiv.tv.
Sun, 26 Jul 2015 15:10:10 +0000
Transgenic pigs resistant to foot-and-mouth disease
Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short interfering RNA (siRNA) and consequently have reduced susceptibility to infection with FMDV. […]
Thu, 23 Jul 2015 20:25:44 +0000
TWiV 346: A double helical career
Episode #346 of the science show This Week in Virology was recorded at the 34th Annual Meeting of the American Society for Virology, where Vincent, Rich, and Kathy spoke with Joan Steitz, a tireless promoter of women in science and one of the greatest scientists of our generation. You can find TWiV #346 at www.twiv.tv.
Sun, 19 Jul 2015 11:04:32 +0000
The Arctic fresh water virome
Although we now understand that viruses are the most abundant organisms on Earth, there are gaps in our knowledge about their distribution in different environments. Results of a new study reveal the diversity and distribution of viruses in Arctic fresh waters. Fresh waters in high latitudes such as the Arctic and Antarctic have low levels […]
Thu, 16 Jul 2015 21:28:09 +0000
TWiV 345: How a vaccine got the nod
On episode #345 of the science show This Week in Virology, the TWiVonauts review how the weather affects West Nile virus disease in the US, benefit of B cell depletion for ME/CFS patients, and an autoimmune reaction induced by influenza virus vaccine that leads to narcolepsy. You can find TWiV #345 at www.twiv.tv.
Sun, 12 Jul 2015 03:31:56 +0000
B cell depletion benefits ME/CFS patients
Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Rituximab is a monoclonal antibody against a protein on the surface of B cells known as CD20. When the antibody is given to […]
Fri, 10 Jul 2015 03:00:48 +0000
TWiV 344: Glasgwegians go viral
Episode #344 of the science show This Week in Virology was recorded at the Glasgow Science Festival microTALKS, where Vincent spoke with Ruth, Glen, and Esther about their research on viruses and Hodgkin lymphoma, adenovirus structure and entry into cells, and interactions between arthropod borne viruses and their hosts. You can find TWiV #344 at www.twiv.tv.
Sun, 05 Jul 2015 14:27:59 +0000
The Wall of Polio, version 3.0
Back in 2013 I built a Wall of Polio in my laboratory – a large stack of six-well cell culture plates that have been used to measure the concentration of polioviruses in various samples by plaque assay. It became a focal point of the lab at which many guests came to have their photographs taken. Sadly, the […]
Thu, 02 Jul 2015 22:12:56 +0000
TWiV 343: The silence of the turnips
On episode #343 of the science show This Week in Virology, the TWiVerinoes discuss the potential for prion spread by plants, global circulation patterns of influenza virus, and the roles of Argonautes and a viral protein in RNA silencing in plants. You can find TWiV #343 at www.twiv.tv.
Sun, 28 Jun 2015 14:39:36 +0000
Small Things Considered
A blog for sharing appreciation of the width and depth of microbes and microbial activities on this planet.
An ongoing phage drama
by Jamie Henzy | Life is full of tough choices. Some of the more dramatic of them play out in the world of bacteria and the phages that infect them...
This Week in Microbiology #108: Vaccine in the time of cholera
The professors of TWiM discuss a University of Wisconsin plan for rescuing biomedical research in the US, and results of a clinical trial in Bangladesh of an oral cholera vaccine.
A Snippet: More Awesome Ocelloid Surprises
by Elio | Not long ago, we posted a piece entitled "The Awesomest Thing in Biology" in which we celebrated the mind-boggling complexities of the ocelloid, an organelle that closely resemble the vertebrate eye – in a unicellular protist! It turns out that further surprises come our way...
Swapping Symbionts Enabled Mediterranean Lichen to Conquer the Arctic
by Jennifer Frazer | In 2003, the Mediterranean coral Oculina patagonica did something that was supposed to be impossible: it destroyed bacteria that had formerly been bleaching and killing it.
Talmudic Question #123
You escape from your lab into the great outdoors for an afternoon, with your new DNA detector in your pocket. You poke about here and there, and find sites where there is a measurable amount of DNA free in solution, say a picogram or more. Where might you be?
To Retract or Not to Retract… That’s the Question
In the previous post I discussed  that editors of Science asked for the retraction of a paper linking XMRV retrovirus to ME/CFS. The decision of the editors was based on the failure of at least 10 other studies to confirm these findings and on growing support that the results were caused by contamination. When the authors refused […]
Tue, 07 Jun 2011 13:34:25 +0000
Science Asks to Retract the XMRV-CFS Paper, it Should Never Have Accepted in the First Place.
Wow! Breaking! As reported in WSJ earlier this week , editors of the journal Science asked Mikovits and her co-authors to voluntary retract their 2009 Science paper . In this paper Mikovits and colleagues of the Whittemore Peterson Institute (WPI) and the Cleveland Clinic, reported the presence of xenotropic murine leukemia virus–related virus (XMRV) in peripheral blood mononuclear cells […]
Thu, 02 Jun 2011 21:34:34 +0000
Does the NHI/FDA Paper Confirm XMRV in CFS? Well, Ditch the MR and Scratch the X… and… you’ve got MLV.
The long awaited paper that would ‘solve’ the controversies about the presence of Xenotropic Murine Leukemia Virus-related virus (XMRV) in patients with chronic fatigue syndrome (CFS) was finally published in PNAS last week . The study, a joint effort of the NIH and the FDA, was withheld, on request of the authors , because it contradicted […]
Mon, 30 Aug 2010 03:32:21 +0000