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About viruses and viral disease
Fri, 07 May 2021 01:14:27 +0000
Trial By Error: My Letters to Psychosomatics Journal About Prof White’s Misleading GETSET Paper
By David Tuller, DrPH In early April, I wrote about a study published in the Journal of Psychosomatic Research—a one-year follow-up of the GETSET trial of self-help graded exercise therapy for ME/CFS. The investigators had previously reported short-term benefits for the intervention. In this new paper, despite no benefits of the intervention over regular care, […]
Fri, 07 May 2021 01:14:27 +0000
Early Immune Responses to Herpes Simplex Virus Type I Infection
Early interactions of herpes simplex virus type 1 with the immune system involve both Langerhans cells and a newly characterized dendritic cell. Understanding the dynamics of these initial interactions of the virus with cells of the immune system may result in better strategies for HSV-1/-2 vaccines.
Thu, 06 May 2021 12:10:19 +0000
Trial By Error: In Guardian Column, Professor Pariante Parrots Standard Biopsychosocial Nonsense
By David Tuller, DrPH On Tuesday (four days ago), The Guardian published an opinion piece from Professor Carmine Pariante titled “Long Covid is very far from ‘all in the mind’–but psychology can still help us to treat it.” The article is the latest from a member of the biopsychosocial ideological brigades to demonstrate what has […]
Sat, 01 May 2021 22:15:28 +0000
Defective genomes modulate respiratory syncytial virus pathogenesis
During viral replication, defective genomes may arise that lack essential sequences. These so-called defective genomes cannot replicate unless they are in the same cell as a helper virus. Defective genomes play a role in modulating pathogenesis of respiratory syncytial virus in humans. Copy-back defective viral genomes (cbDVGs) of RSV arise when the viral RNA polymerase […]
Fri, 30 Apr 2021 00:40:34 +0000
Trial By Error: Professor David’s Third Mis-Citation of Seminal Study of “Medically Unexplained Symptoms”
By David Tuller, DrPH *April is crowdfunding month at Berkeley. I conduct this project as a senior fellow in public health and journalism at the university’s Center for Global Public Health. If you would like to support the project with a donation to Berkeley (tax-deductible for US taxpayers), here’s the place: https://crowdfund.berkeley.edu/project/25504 I have recently blogged […]
Mon, 26 Apr 2021 17:05:33 +0000
Trial By Errors: Why Have Experts in MUS Spent Ten Years Mis-Citing a Study about Costs to the NHS?
By David Tuller, DrPH What does it mean that the top investigators in a field of research have collectively and consistently misrepresented a seminal figure in their purported domain of expertise? I’m talking about all those who present themselves as authorities on the topic of so-called “medically unexplained symptoms” (MUS) but have found it difficult […]
Fri, 23 Apr 2021 20:12:42 +0000
SARS-CoV-2 variants arise during individual infections
Early in the COVID-19 pandemic, SARS-CoV-2 genome variation appeared to be low, with an average of 10 base differences in the 30,000 base genome between any two isolates. Late in 2020, as many more people were infected, variants were isolated that had more changes than previously seen. A study of variation at the genome level […]
Fri, 23 Apr 2021 02:11:47 +0000
Trial By Error: More on the Lightning Process and the Science Media Centre’s Collusion With UK Journalists
By David Tuller, DrPH *April is crowdfunding month at Berkeley. I conduct this project as a senior fellow in public health and journalism at the university’s Center for Global Public Health. If you would like to support the project with a donation to Berkeley (tax-deductible for US taxpayers), here’s the place: https://crowdfund.berkeley.edu/project/25504 My story on the […]
Thu, 22 Apr 2021 05:40:37 +0000
Trial By Error: Do the “Vast Majority” of Lightning Process Participants Achieve “Lasting Change”?
By David Tuller, DrPH Coda Story is an excellent news organization focused on international stories related to the misuse of science and technology, among other topics. Today, it published a piece of mine about the training program called the Lightning Process. Sites devoted to the Lightning Process are full of tales of recovery from prolonged […]
Wed, 21 Apr 2021 06:02:17 +0000
To Retract or Not to Retract… That’s the Question
In the previous post I discussed  that editors of Science asked for the retraction of a paper linking XMRV retrovirus to ME/CFS. The decision of the editors was based on the failure of at least 10 other studies to confirm these findings and on growing support that the results were caused by contamination. When the authors refused […]
Tue, 07 Jun 2011 13:34:25 +0000
Science Asks to Retract the XMRV-CFS Paper, it Should Never Have Accepted in the First Place.
Wow! Breaking! As reported in WSJ earlier this week , editors of the journal Science asked Mikovits and her co-authors to voluntary retract their 2009 Science paper . In this paper Mikovits and colleagues of the Whittemore Peterson Institute (WPI) and the Cleveland Clinic, reported the presence of xenotropic murine leukemia virus–related virus (XMRV) in peripheral blood mononuclear cells […]
Thu, 02 Jun 2011 21:34:34 +0000
Does the NHI/FDA Paper Confirm XMRV in CFS? Well, Ditch the MR and Scratch the X… and… you’ve got MLV.
The long awaited paper that would ‘solve’ the controversies about the presence of Xenotropic Murine Leukemia Virus-related virus (XMRV) in patients with chronic fatigue syndrome (CFS) was finally published in PNAS last week . The study, a joint effort of the NIH and the FDA, was withheld, on request of the authors , because it contradicted […]
Mon, 30 Aug 2010 03:32:21 +0000